2 0 2009 par hed 0 journal Original Parr, D. C.[Daniel C.] Hedwig, G. R.[Gavin R.] Hakin, A. W.[Andrew W.] J. Chem. Eng. Data 2009 2009-02-25 Volumetric Properties of Tripeptides with Polar Side-Chains: Partial Molar Volumes at (288.15 to 313.15) K and Partial Molar Expansions at 298.15 K of Some Peptides of Sequence Gly-X-Gly in Aqueous Solution Solution densities have been determined for aqueous solutions of the tripeptides of sequence glycyl-Xglycine, where X is one of the amino acids serine, threonine, asparagine, glutamine, cysteine, histidine, and tyrosine, at T ) (288.15, 303.15, and 313.15) K. These solution densities were used to calculate the partial molar volumes at infinite dilution, V 2 , for the tripeptides. The V 2 results were combined with those determined in previous work for T ) 298.15 K to obtain the partial molar isobaric expansions at infinite dilution, E 2 {E 2 ) ( YV 2 / YT)p}, for the tripeptides at T ) 298.15 K. The contribution of amino acid side-chain hydration to the E 2 results has been discussed. 10.1021/je800527p 54 606-612 1 water H2O 1 Commercial source 1 Fractional distillation 1 99.99 4 Estimated by the compiler 2 glycyl-L-serylglycine C7H13N3O5 1 Synthesized by the authors 1 99 2 Estimated by the compiler 3 glycyl-L-threonylglycine C8H15N3O5 1 Synthesized by the authors 1 99 2 Estimated by the compiler 4 L-aspartoylbisglycine C8H13N3O6 1 Synthesized by the authors 1 99 2 Estimated by the compiler 5 L-glutamoylbisglycine C9H15N3O6 1 Commercial source 1 Crystallization from solution 1 99 2 Estimated by the compiler 6 glycyl-L-cysteinylglycine C7H13N3O4S 1 Commercial source 1 None used 1 98 2 Estimated by the compiler 7 glycyl-L-histidylglycine C10H15N5O4 1 Synthesized by the authors 1 Crystallization from solution Dried by vacuum heating 1 99 2 Estimated by the compiler 8 glycyl-L-tyrosylglycine C13H17N3O5 1 Synthesized by the authors 1 Crystallization from solution Dried by vacuum heating 1 99 2 Estimated by the compiler 2 1 1 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 2 Liquid 1 2 Temperature, K 1 .06526 4 2 288.15 5 1 1004.947 7 1 .005 1 .06026 4 2 288.15 5 1 1004.509 7 1 .005 1 .05524 4 2 288.15 5 1 1004.055 7 1 .005 1 .05019 4 2 288.15 5 1 1003.609 7 1 .005 1 .06564 4 2 298.15 5 1 1002.841 7 1 .005 1 .0598 4 2 298.15 5 1 1002.335 7 1 .005 1 .05493 4 2 298.15 5 1 1001.905 7 1 .005 1 .05166 4 2 298.15 5 1 1001.615 7 1 .005 1 .04521 4 2 298.15 5 1 1001.047 7 1 .005 1 .06473 4 2 303.15 5 1 1001.336 7 1 .005 1 .06095 4 2 303.15 5 1 1001.005 7 1 .005 1 .0555 4 2 303.15 5 1 1000.528 7 1 .005 1 .05003 4 2 303.15 5 1 1000.051 7 1 .005 1 .06498 4 2 313.15 5 1 997.808 6 1 .005 1 .05935 4 2 313.15 5 1 997.32 6 1 .005 1 .05419 4 2 313.15 5 1 996.891 6 1 .005 1 .04969 4 2 313.15 5 1 996.506 6 1 .005 1 .04543 4 2 288.15 5 1 1003.183 7 1 .005 1 .04107 4 2 288.15 5 1 1002.788 7 1 .005 1 .03542 4 2 288.15 5 1 1002.284 7 1 .005 1 .03014 4 2 288.15 5 1 1001.815 7 1 .005 1 .04024 4 2 298.15 5 1 1000.613 7 1 .005 1 .03505 4 2 298.15 5 1 1000.158 7 1 .005 1 .0306 4 2 298.15 5 1 999.768 6 1 .005 1 .025 4 2 298.15 5 1 999.264 6 1 .005 1 .0453 4 2 303.15 5 1 999.64 6 1 .005 1 .03496 4 2 303.15 5 1 998.733 6 1 .005 1 .02992 4 2 303.15 5 1 998.289 6 1 .005 1 .02533 4 2 303.15 5 1 997.881 6 1 .005 1 .04401 4 2 313.15 5 1 996.025 6 1 .005 1 .03976 4 2 313.15 5 1 995.655 6 1 .005 1 .03329 4 2 313.15 5 1 995.098 6 1 .005 1 .02969 4 2 313.15 5 1 994.793 6 1 .005 1 1 3 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 3 Liquid 1 2 Temperature, K 1 .09131 4 2 288.15 5 1 1007.08 7 1 .003 1 .07941 4 2 288.15 5 1 1006.047 7 1 .003 1 .07023 4 2 288.15 5 1 1005.256 7 1 .003 1 .05962 4 2 288.15 5 1 1004.342 7 1 .003 1 .05602 4 2 288.15 5 1 1004.03 7 1 .003 1 .09143 4 2 303.15 5 1 1003.46 7 1 .003 1 .08055 4 2 303.15 5 1 1002.544 7 1 .003 1 .07099 4 2 303.15 5 1 1001.73 7 1 .003 1 .06908 4 2 303.15 5 1 1001.574 7 1 .003 1 .05146 4 2 303.15 5 1 1000.078 7 1 .003 1 .09325 4 2 313.15 5 1 1000.066 7 1 .003 1 .08221 4 2 313.15 5 1 999.148 6 1 .003 1 .07257 4 2 313.15 5 1 998.353 6 1 .003 1 .06044 4 2 313.15 5 1 997.339 6 1 .003 1 .04964 4 2 313.15 5 1 996.431 6 1 .003 1 .04925 4 2 288.15 5 1 1003.435 7 1 .003 1 .04017 4 2 288.15 5 1 1002.641 7 1 .003 1 .03395 4 2 288.15 5 1 1002.098 7 1 .003 1 .02986 4 2 288.15 5 1 1001.736 7 1 .003 1 .02134 4 2 288.15 5 1 1000.987 7 1 .003 1 .05481 4 2 303.15 5 1 1000.357 7 1 .003 1 .04506 4 2 303.15 5 1 999.529 6 1 .003 1 .03031 4 2 303.15 5 1 998.267 6 1 .003 1 .02019 4 2 303.15 5 1 997.395 6 1 .003 1 .04187 4 2 313.15 5 1 995.778 6 1 .003 1 .03494 4 2 313.15 5 1 995.189 6 1 .003 1 .02986 4 2 313.15 5 1 994.77 6 1 .003 1 .02395 4 2 313.15 5 1 994.263 6 1 .003 1 1 4 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 4 Liquid 1 2 Temperature, K 1 .06951 4 2 288.15 5 1 1005.982 7 1 .0005 1 .06457 4 2 288.15 5 1 1005.5 7 1 .0005 1 .05974 4 2 288.15 5 1 1005.028 7 1 .0005 1 .05155 4 2 288.15 5 1 1004.231 7 1 .0005 1 .04516 4 2 288.15 5 1 1003.597 7 1 .0005 1 .03979 4 2 288.15 5 1 1003.071 7 1 .0005 1 .03248 4 2 288.15 5 1 1002.34 7 1 .0005 1 .02634 4 2 288.15 5 1 1001.735 7 1 .0005 1 .05892 4 2 298.15 5 1 1002.802 7 1 .003 1 .05367 4 2 298.15 5 1 1002.289 7 1 .003 1 .0486 4 2 298.15 5 1 1001.8 7 1 .003 1 .04282 4 2 298.15 5 1 1001.244 7 1 .003 1 .03757 4 2 298.15 5 1 1000.729 7 1 .003 1 .0337 4 2 298.15 5 1 1000.352 7 1 .003 1 .03159 4 2 298.15 5 1 1000.147 7 1 .003 1 .02795 4 2 298.15 5 1 999.79 6 1 .003 1 .02484 4 2 298.15 5 1 999.489 6 1 .003 1 .02287 4 2 298.15 5 1 999.295 6 1 .003 1 .06187 4 2 303.15 5 1 1001.639 7 1 .003 1 .0554 4 2 303.15 5 1 1001.019 7 1 .003 1 .04971 4 2 303.15 5 1 1000.473 7 1 .003 1 .0429 4 2 303.15 5 1 999.814 6 1 .003 1 .03772 4 2 303.15 5 1 999.316 6 1 .003 1 .0319 4 2 303.15 5 1 998.757 6 1 .003 1 .02783 4 2 303.15 5 1 998.36 6 1 .003 1 .02508 4 2 303.15 5 1 998.095 6 1 .003 1 .02228 4 2 303.15 5 1 997.821 6 1 .003 1 .06187 4 2 313.15 5 1 998.14 6 1 .003 1 .0554 4 2 313.15 5 1 997.526 6 1 .003 1 .04971 4 2 313.15 5 1 996.987 6 1 .003 1 .0429 4 2 313.15 5 1 996.336 6 1 .003 1 .03772 4 2 313.15 5 1 995.842 6 1 .003 1 .0319 4 2 313.15 5 1 995.29 6 1 .003 1 .02783 4 2 313.15 5 1 994.898 6 1 .003 1 .02508 4 2 313.15 5 1 994.635 6 1 .003 1 .02228 4 2 313.15 5 1 994.368 6 1 .003 1 1 5 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 5 Liquid 1 2 Temperature, K 1 .06734 4 2 288.15 5 1 1005.83 7 1 .003 1 .0578 4 2 288.15 5 1 1004.881 7 1 .003 1 .04626 4 2 288.15 5 1 1003.744 7 1 .003 1 .05656 4 2 303.15 5 1 1001.186 7 1 .003 1 .05226 4 2 303.15 5 1 1000.764 7 1 .003 1 .04429 4 2 303.15 5 1 999.99 6 1 .003 1 .04323 4 2 303.15 5 1 999.88 6 1 .003 1 .05656 4 2 313.15 5 1 997.683 6 1 .003 1 .05226 4 2 313.15 5 1 997.267 6 1 .003 1 .04323 4 2 313.15 5 1 996.398 6 1 .003 1 .04216 4 2 288.15 5 1 1003.333 7 1 .003 1 .03159 4 2 288.15 5 1 1002.275 7 1 .003 1 .02725 4 2 288.15 5 1 1001.836 7 1 .003 1 .04087 4 2 303.15 5 1 999.656 6 1 .003 1 .03622 4 2 303.15 5 1 999.207 6 1 .003 1 .03193 4 2 303.15 5 1 998.782 6 1 .003 1 .03003 4 2 303.15 5 1 998.601 6 1 .003 1 .03622 4 2 313.15 5 1 995.724 6 1 .003 1 .03193 4 2 313.15 5 1 995.319 6 1 .003 1 .03003 4 2 313.15 5 1 995.134 6 1 .003 1 1 6 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 6 Liquid 1 2 Temperature, K 1 .04953 4 2 288.15 5 1 1003.707 7 1 .003 1 .04442 4 2 288.15 5 1 1003.233 7 1 .003 1 .04097 4 2 288.15 5 1 1002.915 7 1 .003 1 .0395 4 2 288.15 5 1 1002.783 7 1 .003 1 .03474 4 2 288.15 5 1 1002.336 7 1 .003 1 .05296 4 2 303.15 5 1 1000.429 7 1 .003 1 .05003 4 2 303.15 5 1 1000.168 7 1 .003 1 .04358 4 2 303.15 5 1 999.593 6 1 .003 1 .04008 4 2 303.15 5 1 999.279 6 1 .003 1 .0374 4 2 303.15 5 1 999.043 6 1 .003 1 .05751 4 2 313.15 5 1 997.331 6 1 .003 1 .05218 4 2 313.15 5 1 996.867 6 1 .003 1 .05002 4 2 313.15 5 1 996.672 6 1 .003 1 .04508 4 2 313.15 5 1 996.242 6 1 .003 1 .02984 4 2 288.15 5 1 1001.884 7 1 .003 1 .02582 4 2 288.15 5 1 1001.513 7 1 .003 1 .02087 4 2 288.15 5 1 1001.053 7 1 .003 1 .01633 4 2 288.15 5 1 1000.629 7 1 .003 1 .03394 4 2 303.15 5 1 998.731 6 1 .003 1 .03046 4 2 303.15 5 1 998.417 6 1 .003 1 .02788 4 2 303.15 5 1 998.184 6 1 .003 1 .02497 4 2 303.15 5 1 997.92 6 1 .003 1 .02103 4 2 303.15 5 1 997.568 6 1 .003 1 .03941 4 2 313.15 5 1 995.739 6 1 .003 1 .03597 4 2 313.15 5 1 995.437 6 1 .003 1 .03109 4 2 313.15 5 1 995.001 6 1 .003 1 .02094 4 2 313.15 5 1 994.099 6 1 .003 1 1 7 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 7 Liquid 1 2 Temperature, K 1 .01205 5 2 288.15 5 1 1000.307 7 1 .005 1 .010884 5 2 288.15 5 1 1000.191 7 1 .005 1 .010119 5 2 288.15 5 1 1000.112 7 1 .005 1 .00901 4 2 288.15 5 1 1000.003 7 1 .005 1 .008127 4 2 288.15 5 1 999.911 6 1 .005 1 .012267 5 2 298.15 5 1 998.254 6 1 .005 1 .011091 5 2 298.15 5 1 998.142 6 1 .005 1 .01009 5 2 298.15 5 1 998.038 6 1 .005 1 .00901 4 2 298.15 5 1 997.939 6 1 .005 1 .012247 5 2 303.15 5 1 996.842 6 1 .005 1 .011058 5 2 303.15 5 1 996.73 6 1 .005 1 .007975 4 2 303.15 5 1 996.427 6 1 .005 1 .00711 4 2 303.15 5 1 996.346 6 1 .005 1 .012322 5 2 313.15 5 1 993.4 6 1 .005 1 .011384 5 2 313.15 5 1 993.309 6 1 .005 1 .010224 5 2 313.15 5 1 993.207 6 1 .005 1 .0082 4 2 313.15 5 1 993.012 6 1 .005 1 .007051 4 2 288.15 5 1 999.802 6 1 .005 1 .006072 4 2 288.15 5 1 999.708 6 1 .005 1 .00501 4 2 288.15 5 1 999.6 6 1 .005 1 .004019 4 2 288.15 5 1 999.501 6 1 .005 1 .008041 4 2 298.15 5 1 997.838 6 1 .005 1 .007226 4 2 298.15 5 1 997.762 6 1 .005 1 .004009 4 2 298.15 5 1 997.442 6 1 .005 1 .006103 4 2 303.15 5 1 996.247 6 1 .005 1 .00498 4 2 303.15 5 1 996.138 6 1 .005 1 .00404 4 2 303.15 5 1 996.046 6 1 .005 1 .006936 4 2 313.15 5 1 992.89 6 1 .005 1 .006051 4 2 313.15 5 1 992.804 6 1 .005 1 .005108 4 2 313.15 5 1 992.711 6 1 .005 8 1 1 1 Principal objective of the work KRP TRC 2/20/2009 1 Mass density, kg/m3 Vibrating tube method Liquid Direct value, X 1 Author Liquid Pressure, kPa 101 3 1 Molality, mol/kg 8 Liquid 1 2 Temperature, K 1 .02909 4 2 288.15 5 1 1002.058 7 1 .003 1 .0279 4 2 288.15 5 1 1001.946 7 1 .003 1 .02705 4 2 288.15 5 1 1001.853 7 1 .003 1 .02575 4 2 288.15 5 1 1001.724 7 1 .003 1 .02504 4 2 288.15 5 1 1001.65 7 1 .003 1 .02882 4 2 303.15 5 1 998.496 6 1 .003 1 .02792 4 2 303.15 5 1 998.415 6 1 .003 1 .02701 4 2 303.15 5 1 998.323 6 1 .003 1 .02604 4 2 303.15 5 1 998.224 6 1 .003 1 .02501 4 2 303.15 5 1 998.127 6 1 .003 1 .02396 4 2 303.15 5 1 998.023 6 1 .003 1 .02902 4 2 313.15 5 1 995.047 6 1 .003 1 .02763 4 2 313.15 5 1 994.913 6 1 .003 1 .02688 4 2 313.15 5 1 994.842 6 1 .003 1 .02586 4 2 313.15 5 1 994.742 6 1 .003 1 .02492 4 2 313.15 5 1 994.655 6 1 .003 1 .02376 4 2 313.15 5 1 994.546 6 1 .003 1 .02384 4 2 288.15 5 1 1001.531 7 1 .003 1 .023 4 2 288.15 5 1 1001.449 7 1 .003 1 .02117 4 2 288.15 5 1 1001.261 7 1 .003 1 .01938 4 2 288.15 5 1 1001.081 7 1 .003 1 .01708 4 2 288.15 5 1 1000.848 7 1 .003 1 .02301 4 2 303.15 5 1 997.932 6 1 .003 1 .02087 4 2 303.15 5 1 997.719 6 1 .003 1 .019 4 2 303.15 5 1 997.535 6 1 .003 1 .01781 4 2 303.15 5 1 997.42 6 1 .003 1 .01685 4 2 303.15 5 1 997.325 6 1 .003 1 .02288 4 2 313.15 5 1 994.456 6 1 .003 1 .0216 4 2 313.15 5 1 994.332 6 1 .003 1 .02086 4 2 313.15 5 1 994.259 6 1 .003 1 .01889 4 2 313.15 5 1 994.065 6 1 .003 1 .01785 4 2 313.15 5 1 993.972 6 1 .003 1 .017 4 2 313.15 5 1 993.889 6 1 .003